CGP77675 hydrate '-diphosphate Toxicity of the mitochondrial poison

Toxicity of the mitochondrial poison dequalinium chloride in a murine model system

InChiKey: ZTHJULTYCAQOIJ-QRQSOFFPSA-N

InChiKey: URVRJYLSUVXWBC-AATRIKPKSA-N

CAS Number: 122341-38-2

3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)acetamide

CGP77675 hydrate '-diphosphate Toxicity of the mitochondrial poisonCGP77675 hydrate is an orally active and potent inhibitor of Src family kinases. CGP77675 hydrate inhibits phosphorylation of peptide substrates and autophosphorylation of purified Src (IC50s of 5 20 and 40 nM, respectively),and also inhibits Src, EGFR, KDR, v Abl, and Lck with IC50s of 0. 02, 0. 15, 1. 0, 0. 31, and 0. 29 M, respectively. Anticancer activity. Product information Molecular Weight: 461. 56 Formula: C26H31N5O3 Chemical Name: 1 (4 (4