![Eg5 Inhibitor III - CAS# 863774-58-7 Catalog No.:M6537-2 Smiles: [O-][N@@+]12CCC[C@H]3CN4[C@H](CCCC4=O)[C@@H](CCC1)[C@@H]23](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/Dimethylenastron.gif?v=1742660641)
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Smiles: [O-][N@@+]12CCC[C@H]3CN4[C@H](CCCC4=O)[C@@H](CCC1)[C@@H]23
Felbamate has been proposed to a unique dual mechanism of action as a positive modulator of GABAA receptors and as a blocker of NMDA receptors
MLN8237 induced polyploidization and expression of mature megakaryocyte markers in acute megakaryocytic leukemia (AMKL) blasts and displayed potent anti-AMKL activity in vivo
PubMed PMID: 21258765
which mimics the binding of DAG
Eg5 Inhibitor III - CAS# 863774-58-7 Catalog No.:M6537-2 Smiles: [O-][N@@+]12CCC[C@H]3CN4[C@H](CCCC4=O)[C@@H](CCC1)[C@@H]23Eg5 Inhibitor III, CAS No. 863774 58 7, is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Eg5 Inhibitor III suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5. The inhibition of kinesin Eg5 by small molecules such as monastrol is currently evaluated as an approach to develop a novel class of antiproliferative drugs for the treatment of malignant tumours. Product
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