2', 3', 5'-triacetyl-5-Azacytidine Size:Contact [email protected] for quotation Selective and Cell-Active Allosteric Inhibitor

Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)

CAS Number: 845932-30-1

InChi: InChI=1S/C24H25ClFN5O2/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31/h5-8

Chemical Name: 4-amino-N-(4

CAS Number: 10161-34-9

2', 3', 5'-triacetyl-5-Azacytidine Size:Contact [email protected] for quotation Selective and Cell-Active Allosteric Inhibitor2',3',5' triacetyl 5 Azacytidine (TAC) is the lead prodrug form of 5 azacytidine which may be rapidly absorbed after oral administration . 5 Azacytidine is an inhibitor of DNA methyltransferase . The DNA methyltransferase belongs to a family of enzymes involved in catalyzing the transfer of a methyl group to DNA. DNA methylation has been implicated in regulating gene expression in normal and malignant cells . In vivo: In CD 1 mice, oral administration