AM-2394 II Degrader-3 In the HCT-116 tumor-bearing mice

In the HCT-116 tumor-bearing mice

(S)-Hydroxychloroquine ((S)-HCQ) is the enantiomer of Hydroxychloroquine

Chemical Name: N-(4-((6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl)amino)phenyl)benzamide

CAS Number: 377090-84-1

In the presence of 1% serum

AM-2394 II Degrader-3 In the HCT-116 tumor-bearing miceAM 2394 is a structurally distinct glucokinase activator (GKA). AM 2394 activates glucokinase (GK) with an EC50 of 60 nM. Product information CAS Number: 1442684 77 6 Molecular Weight: 423. 47 Formula: C22H25N5O4 Chemical Name: 1 [6' (2 hydroxy 2 methylpropoxy) 4 [(5 methylpyridin 3 yl)oxy] [3,3' bipyridin] 6 yl] 3 methylurea Smiles: CC1C=C(C=NC=1)OC1C=C(NC(=O)NC)N=CC=1C1C=NC(=CC=1)OCC(C)(C)O InChiKey: QUISANLDBDCMPD UHFFFAOYSA N InChi: InChI=1S